In this episode, Dr. Eric Osansky explores a common question he receives from people with hyperthyroidism: Can I incorporate intermittent fasting? While fasting has been praised for benefits such as weight loss, blood sugar regulation, reduced inflammation, and improved metabolic health, Dr. Eric explains why those with hyperthyroidism and Graves’ disease need to approach fasting differently than the general population.
Dr. Eric reviews the most common fasting methods, including overnight fasting, 16:8 intermittent fasting, alternate-day fasting, water fasting, and fasting-mimicking diets. He explains how hyperthyroidism creates a catabolic state characterized by increased metabolism, muscle breakdown, and weight loss, making prolonged fasting potentially problematic for some people. He also discusses the important roles of adrenal health, cortisol balance, blood sugar regulation, insulin resistance, and stress when determining whether fasting is appropriate.
Throughout the episode, Dr. Eric emphasizes the importance of individualization. While fasting may offer benefits for certain people, especially those with stable thyroid levels and insulin resistance, it may be counterproductive for others who are actively hyperthyroid, losing weight, struggling with adrenal dysfunction, or experiencing significant symptoms. If you want a balanced, practical perspective on fasting and hyperthyroidism, you’ll get a lot out of this episode.
Click Here to listen to it on the Save My Thyroid podcast
Dr. Eric Osansky:
Intermittent fasting has become incredibly popular over the last decade. Some people swear by it for weight loss, blood sugar balance, inflammation, even longevity. But if you have hyperthyroidism, including Graves’ or toxic multinodular goiter, the question is: Should you be fasting?
The answer isn’t necessarily yes or no. In some cases, fasting can be helpful while in others it can slow down your recovery.
What you need to keep in mind is that when it comes to fasting, most of the fasting advice is directed toward a general population. There isn’t a lot out there when it comes to hyperthyroidism and fasting, at least not in the research. People with hyperthyroidism, they do have unique consideration.
Remember there is not a one size fits all approach. If you’re reading a book on intermittent fasting, for example, or watching YouTube videos, keep in mind that the people who are talking about it usually are not dealing with hyperthyroidism. That does make a big difference.
Let’s briefly talk about the different types of fasting. I won’t go into great detail here. You can learn more about this elsewhere.
The most basic type is an overnight 12-hour fast, where you stop eating at 7pm and then eat the next morning at 7am, for example. You can vary that. Maybe you stop eating at 6pm and eat at 6am. You could do a 14-hour fasting window. Very popular is 16-8 fasting, where you’re fasting for 16 hours, and you have an 8-hour eating window.
There is alternate day fasting. There is 24-hour fasting. There is multiple-day fasting. There is water fasting.
There is also what’s called fasting mimicking diets. The goal is to replace the benefits of intermittent fasting without restricting the eating that is associated with traditional fasting. Essentially, it allows a limited intake of specific nutrients to help sustain the body. Usually, you are following this diet over a five-day period. Many times, people will do it once a month for a few consecutive months.
As far as why people are interested in fasting, there are numerous benefits. The #1 reason is weight loss. People want to lose weight. When I dealt with hyperthyroidism, I did not want to lose weight. I was losing too much weight. I would have not been a good fit for intermittent fasting. There are some people with hyperthyroidism who aren’t losing weight. That is one of the potential benefits.
Blood sugar regulation. If someone is dealing with insulin resistance, type 2 diabetes.
Inflammation. Some will talk about fasting, including intermittent fasting, for reducing inflammation, especially if someone has autoimmune conditions. It could be a piece of the puzzle. I would keep your expectations in check. Fasting alone is probably not going to completely eliminate the inflammation. Maybe it will reduce it to some extent. Maybe not. Depends on the person.
There is what’s called autophagy, which is cellular cleanup, improving metabolic flexibility, which is the body’s ability to shift between burning glucose and fat for energy. Those are probably the main benefits. I’m sure there are others. Giving your digestive system a rest would be a potential benefit of intermittent fasting.
Why is fasting more challenging with hyperthyroidism? The reason is because hyperthyroidism is considered to be a catabolic state. Catabolism means you have increased muscle breakdown, typically weight loss, and increased metabolic rate. If you have an elevated resting heart rate, like I did when dealing with Graves’.
Sometimes, it’s strange just because you figure if you have that increased metabolism, you will lose weight. A lot of people do lose weight. Weight loss is very common. But there is a decent amount of people who don’t lose weight, even if they have an increased resting heart rate. They also might be losing muscle mass, even if they are not losing weight. The classic hyperthyroid case, you not only have the increased metabolic rate, but you also have muscle breakdown as well as weight loss. I fell under that category when I dealt with Graves’. Not everybody does.
The concern with fasting, if you are in that state of catabolism already, that fasting may already further increase the tissue breakdown in people with hyperthyroidism who are losing weight, losing muscle. When you have hyperthyroidism, you might need more calories. The key is not just getting more calories, but with any health condition, make sure you are eating healthy foods, nutrient dense foods.
A problem with fasting, even intermittent fasting, is some people aren’t getting enough calories. If you are doing a 12-hour fast or a 14-hour fast, you are probably fine. Even if you are doing a 16-8 fast, it might be okay. Over the years, I have had people do 20-hour fasts every single day. Only a four-hour eating window. When that’s the case, they are probably not getting enough calories or nutrients or protein.
Anything over 16-8 is a bit extreme if you’re doing it every single day, especially if you’re dealing with hyperthyroidism. Not to say 16-8 is acceptable for everyone. You need to be careful if you’re dealing with hyperthyroidism, which you probably are if you’re listening to this.
Remember, everyone is different. Not everyone has classic hyperthyroid signs and symptoms, including weight loss. If that’s the case, maybe you can get away with the 16-8 fast. Maybe you could get some benefits from a 16-8 fast. If you are losing a lot of weight, a lot of muscle, with that increased metabolism, then 16-8 or even 14 hours might be too extreme for you. Everyone is different.
In addition, we need to look at the adrenals, blood sugar. When it comes to cortisol and hyperthyroidism, a lot of people with hyperthyroidism have cortisol imbalances. I know I did when I dealt with Graves’. I had low cortisol, but some people have high cortisol. The only way to know for sure is by testing.
Blood sugar imbalances are very common. You could test not just fasting glucose; that’s what most doctors do. It’s great if you test fasting glucose, but you also want to test fasting insulin and hemoglobin A1C, which is the average blood glucose over a period of 2-4 months. I wouldn’t look at any one of these alone. Do all three. There are other blood sugar markers. At the very least, do fasting glucose, fasting insulin, and hemoglobin A1C.
In some cases, some people will get what’s called a continuous glucose monitor (CGM), which is constantly looking at glucose levels throughout the day. Usually, you tie it into an app. I have tried that out for a few weeks. Working with a practitioner is a good idea if you’re using one. Usually, you will need a prescription for one anyway. These days, there are companies where you can purchase on your own. Many times, you will need to work with someone.
Cortisol imbalances are a big issue. The reason is stress is a big factor. Chronic stress is a big factor. The reason I am bringing this up is because intermittent fasting can be a stressor as well. Not everybody perceives it as being a stressor. It’s one of these things where it could be a physiological stressor, especially if you are doing extreme fasting. I mentioned someone who is fasting 20 hours a day with a four-hour eating window, or an 18-6 fast, where you fast for 18 hours and eat for six hours. That could put stress on your body.
From a psychological standpoint, the perception of stress also could be difficult. If you only have that 4-6-hour eating window, psychologically, some people might be fine with that. That could also affect stress from an emotional standpoint.
If you are dealing with something like insulin resistance, fasting without question can improve insulin sensitivity in people. You also need to consider the impact it has on your adrenals.
You also need to see how you feel. If you’re doing intermittent fasting, even if you are doing a 16-8 fast, and you’re experiencing increased anxiety, increased shakiness, palpitations. I know these are common symptoms with hyperthyroidism. I’m saying if it seems more extreme with the fasting. Getting disrupted sleep. Any exacerbation of symptoms when you start fasting, maybe that’s telling you that it’s a little bit too extreme. You want to listen to your body.
I already mentioned a few situations when you want to be cautious about intermittent fasting when you’re dealing with hyperthyroidism. If you’re having extremely elevated thyroid hormones, or even if they are moderately elevated, they don’t have to be off the charts. Even without looking at your thyroid hormones, if you’re losing weight and muscle, it may not be a good idea to do longer fasts.
If you’re one of those people with hyperthyroidism where you’re not losing weight, maybe even having difficulty losing weight, but still moderate to severely hyperthyroid, which it doesn’t make sense but does happen in some cases, if your thyroid hormones are extremely elevated, you also might want to be cautious about doing intermittent fasting. 12-14 hours is okay for most people, but going beyond that, I would work with a healthcare practitioner.
I already mentioned if you’re having weight loss, especially significant weight loss, I lost 42 pounds total when I dealt with Graves’. I mentioned muscle wasting. If you’re having blood sugar imbalances. If you’re having insulin resistance, intermittent fasting could help in some cases. If you are having hypoglycemia, low blood sugar, it’s probably not a good idea to incorporate intermittent fasting.
Listen to your body. If you’re having increased anxiety, sleep issues. There are other common scenarios, like if someone is pregnant, then you probably don’t want to do extreme fasting. I wouldn’t say 16-8 fasting is extreme, but I would definitely work with a practitioner if you plan on doing that and are pregnant. If you are pregnant, you want to make sure you get enough nutrients for you and the baby that you get through food. If you are only eating 4-6 hours a day, even eight hours a day, that still might not be enough if pregnant.
When is fasting considered reasonable for those who have hyperthyroidism? If your thyroid levels have stabilized, if you are not actively hyperthyroid- I am not giving recommendations and saying if everything looks good, go ahead and fast. But that’s one scenario where fasting might be okay.
Adrenal health. Healthy adrenals. Doing an adrenal saliva panel or maybe a dried urine test, like the DUTCH test. Looking not just at a single cortisol level but cortisol levels throughout the day. Blood sugar, looking at glucose, insulin, hemoglobin A1C.
You should also have a healthy relationship with food. Fasting should not become another source of stress. If you’re stressed out because you’re fasting, and I mentioned this earlier, it could be physiological stressors, but it could be emotional stressors. The fasting itself could be a stressor. That is probably not a good idea if that increases stress.
When it comes to specifically Graves’, there are some practitioners out there who talk about fasting helping with autoimmunity, with the immune system response. It could reduce inflammation, modulate the immune system. Fasting can have these benefits.
Autoimmune hyperthyroidism is different. I don’t want to keep on repeating myself. If you’re dealing with Graves’, yet you’re losing a lot of weight, you’re losing a lot of muscle, your adrenals aren’t great, then everything comes down to risk versus benefit. Fasting might still offer some benefit with the autoimmune component.
I don’t even want to say it’s a piece of the puzzle. I talk about how diet is a piece of the puzzle. For example, when I dealt with Graves’, I didn’t do any fasting. My situation is different than yours. If someone is dealing with Graves’, and they are having difficulty losing weight, then maybe in that case, fasting would be okay. It also depends. If your adrenals are not in great shape, it could be an increased stressor. Of course, I will be biased because I am a natural healthcare practitioner, but I recommend working with someone and not doing this on your own.
Hyperthyroidism is complex. Autoimmunity is complex. Autoimmune conditions such as Graves’ are complex. Especially when it comes to Graves’, it’s finding and removing triggers: food triggers, environmental toxins and toxicants, gut infections, chronic stress, correcting nutrient deficiencies, healing the gut. All of these are important. If all you do is intermittent fasting, you are not going to reverse Graves’.
I will say that many people over the years have reversed Graves’ without intermittent fasting. I can’t say that fasting is necessary in most people with hyperthyroidism and Graves’. It could offer some benefits in some situations, but you want to be careful. Work with someone. Remember that fasting alone is definitely not a treatment for Graves’ or any other type of hyperthyroidism.
I would say start out more conservatively. If you haven’t done anything when it comes to fasting, or even if you have, if you have been doing extreme fasting, cut back. I would recommend for those who haven’t done anything to start with a 12-hour overnight fast. If you have been fasting for 20 hours a day, and you don’t want to cut back to 12 hours, maybe 14 hours. Finish dinner at 6/7pm. Eat breakfast at 6/7am. If you were to stop eating dinner at 6pm and eat breakfast at 8am, which is 14 hours, most people can handle that as well.
Everyone is unique. If someone has hypoglycemia, you might not want to do that. Not everybody with hypoglycemia is the same.
Start with a 12-hour fast. Consider gradually progressing to 13-14 hours. Pay careful attention to any symptoms you’re experiencing. If you’re experiencing any increase in symptoms. I mentioned specifically anxiety, palpitations, poor sleep, increased fatigue. Obviously things like dizziness are not good. Listen to your body. Don’t try to tough it out when it comes to fasting.
Keep in mind there are alternatives. Focusing on eating nutrient-dense foods, plenty of protein, healthy fats, fiber. Reduce snacking. Maybe rather than doing a fast, have specific eating windows. Don’t snack. Have three meals per day. Make sure all the meals that you eat are nutrient dense, healthy meals.
Block out time for stress management. Prioritize sleep. These are all important. Many people can achieve really good health benefits without doing aggressive fasting. As I mentioned, I don’t know if I would consider 16-8 fasting to be aggressive, but it depends. Someone with active hyperthyroidism, especially if you are losing weight, muscle mass, then I would say 16-8- When I dealt with Graves’, 16-8 fasting would have been too aggressive for me. Not everybody is in that same situation, but a lot of people are.
If you’re experiencing moderate to severe hyperthyroidism, especially weight loss, muscle loss, be cautious when it comes to fasting. Like I said, you also have to look at other things like blood sugar markers, adrenals.
I am not against fasting. This solo episode might give you the impression that I am not a big fan of fasting. I have done 16-8 fasting. Most nights, I am usually doing 14-hour fasts. At least 12-14 hours. Sometimes, I do 16-8 fasts. I did it more frequently in the past. Now, I just listen to my body. A few years ago, I would stop eating at 6pm and eat again at 10am the next morning. If I’m hungry, I won’t wait just to go 16 hours. I will eat if I’m hungry after 12 hours or 14 hours.
Focus on healing right now. You don’t need to fast in order to heal. Maybe later on, you introduce it. Or start with 12 hours and gradually increase to 13, 14 hours.
My point is, don’t force fasting. Don’t fast because it’s popular, and you have friends who are doing it or hear about others doing it.
I’ll wrap things up. Fasting is not necessarily good or bad for people with Graves’ and other types of hyperthyroidism. If you have active hyperthyroidism, if you’re losing weight, if you’re losing muscle, have unstable blood sugar levels, blood sugar imbalances, compromised adrenals, you want to be careful about doing more than 12-14 hours’ worth of fasting.
A 12-hour overnight fast is a reasonable starting point. Just because fasting can be beneficial for some people doesn’t mean it’s beneficial for others. The question isn’t whether fasting is healthy. The question is whether it’s healthy for you, based on where you are in your hyperthyroid healing journey.
I also put together a few questions people might have. One question some people have every now and then is: Can fasting lower thyroid hormone or thyroid antibodies? I will say there is some evidence that restricting calories extremely can actually lower thyroid hormones. It’s not the way you want to go about it. You don’t want to do extreme fasting. That’s not addressing the cause of the hyperthyroidism. In some cases, fasting might be able to help lower thyroid hormone levels. It’s not going to do much from an autoimmune component as far as lowering thyroid antibodies.
Can fasting help with weight gain in Graves’? Maybe. It depends. Not everybody is the same. If someone is having insulin resistance and Graves’, maybe. I would say work with a healthcare practitioner.
Is fasting different for Hashimoto’s’ versus Graves’? Those with Hashimoto’s usually aren’t losing weight. Many people with Graves’ are losing weight, but a lot of people with Hashimoto’s have adrenal imbalances and blood sugar imbalances. If it’s blood sugar imbalances like insulin resistance, maybe it’s okay. If it’s hypoglycemia, maybe not. If someone has compromised adrenals regardless of whether they have Graves’ or Hashimoto’s or a different autoimmune condition, you want to be cautious.
You can learn more about diet by reading my book The Hyperthyroid Healing Diet. I don’t talk a lot about fasting in it, but it’s in there a little bit. My Healing Graves’ Naturally newsletter, SaveMyThyroid.com/GravesNewsletter.
Like I said, I will always recommend working with a healthcare practitioner, usually a natural one. If you go to your primary care doctor or your endocrinologist, they are probably not going to be big fans of fasting. In all likelihood, they will tell you that diet won’t make any difference when it comes to your hyperthyroid condition. You probably don’t want to bring up diet at all to your endocrinologist.
I am not against intermittent fasting, especially in a healthier state. If you are healing, you want to be cautious.
Thanks again for tuning in. Look forward to catching you in the next episode.
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Hopefully, you found this solo episode on fasting and hyperthyroidism to be helpful. Over the years, I have had a number of people ask me about water fasts on hyperthyroidism. Three-day fasts, if not five-day fasts.
I don’t usually recommend this for some of the same reasons I mentioned during the episode. If someone is losing a lot of weight, you don’t want to do this. Even if you are not losing a lot of weight, it puts a lot of stress on the body.
Everything is risk versus benefit. If someone is in a healthier state, they are dealing with insulin resistance, maybe the benefits very well might outweigh the risks. Even if someone is not losing weight, maybe you have problems losing weight. If your adrenals aren’t in great shape, then I’m not sure if you want to do a three-day water fast, let alone a five-day water fast.
24-hour water fast? I wouldn’t do them regularly. It’s different if you’re in a better state of health. That’s why people are trying to incorporate water fasting and juice fasting to try to get into a healthier state, to help benefit their health. You definitely want to be careful. Work with someone.
If you are working with me, just to be up front, I wouldn’t recommend a three-day water fast or regular 24-hour fasting. If you are looking to do those, you wouldn’t want to work with me because I won’t tell you to do those types of fasts.
Fasting and insulin resistance. I spoke about this a little bit during the episode. If someone has insulin resistance and hyperthyroidism, and they are not losing weight, intermittent fasting, 12-14 hours is something to consider. 16-8, maybe in the case where someone is not losing weight.
It depends on the state of your adrenals, which is why I would recommend doing an adrenal saliva test or dried urine test to look at the circadian rhythm of cortisol. That would be a situation where I would at least consider it.
If someone has insulin resistance and hyperthyroidism, whether it’s Graves’ or toxic multinodular goiter, and they are struggling to lose weight, and maybe their adrenals don’t look too bad, maybe doing a 16-8 fast is something they could do. Keep in mind it doesn’t work with everybody. Fasting can sometimes work wonders, but sometimes there are other things you need to do.
With insulin resistance, there is an inflammatory component, so you might need to do other things to reduce inflammation.
Fasting as a source of stress. I mentioned this already. Tying it into the adrenals. Fasting itself could be a stressor. I mentioned if you already have weakened adrenals, you might want to be careful about fasting.
Also, fasting itself could be a stressor in some people. Some people are excited about fasting. They think about this positively. Others learn about fasting and are not happy about it, but they are doing it to try to lose weight or general health benefits. Maybe they heard it can help with the immune system, which I’ll discuss next. Especially if you have a negative mindset toward fasting, and then you’re doing it, just like you have a negative mindset toward AIP or any diet, it could be a big emotional stressor.
It could be a big physical stressor, too, if your body is not ready for it. If you are losing weight and/or your adrenals are compromised.
I am not trying to talk negatively about fasting, but I am warning you. I have done 16-8 fasting. I regularly do 12-14-hour fasts. I know people who do more extreme fasting, and it’s benefited them. You just want to be careful. Hyperthyroidism is different than many other health conditions.
Finally, can fasting benefit autoimmunity? There are practitioners talking about the benefits of it. I discussed this a little bit during the episode. All I’ll say is it could in some cases benefit the immune system. I also can’t say it’s necessary.
There are a lot of things out there that can add benefits. Doing hyperbaric oxygen might have benefits. That is a little bit more extreme because you’d have to go somewhere or buy your own hyperbaric oxygen chamber. Fasting is simple and easy. Could put stress on your body, but it is definitely easier than some other things.
I wouldn’t say it’s absolutely necessary. I have had a lot of success over the years helping people with hyperthyroidism, Graves’, toxic multinodular goiter, without recommending fasting. I can’t say that I’m going to recommend fasting. I’ve mentioned this already. Everyone is different. There definitely are benefits of fasting and caloric restriction. Most of the studies on fasting and caloric restriction are more animal studies. It doesn’t mean there are not benefits with humans. Like I said, really be careful. If you really are thinking about it, work with someone.
The problem is, if you work with someone, it probably won’t be someone who is too familiar with hyperthyroidism. I honestly don’t know anyone who focuses on hyperthyroidism and also has a lot of experience with fasting. You might be on your own. If you are working with someone who has a lot of experience with fasting, they could do some of their own research.
If you work with someone who has a lot of experience with fasting, not with hyperthyroidism specifically, and they tell you, “I’m not sure. Maybe I wouldn’t do it in your situation,” that’s a red flag. If someone who is an advocate of fasting is telling you that maybe you shouldn’t fast, you want to be cautious.
With me, I am neutral. I am not against fasting. I am just cautious. If you work with someone who recommends fasting on a regular basis, and they are not sure in your situation, then you might want to think twice about doing it, at least while healing. Maybe in the future, you probably could do it. While healing, maybe don’t do it.
That’s all I want to talk about with regard to fasting. As usual, hope you found this information to be valuable. Look forward to catching you in the next episode.

